The intended use of calibration in the DFE is to return your device to the state that the reference printer was in when ICC color profiles were made. This will allow you to get a professional color result from your printer without doing the ICC profiling yourself.
Choose the most appropriate profile from the list and calibrate your printer to that standard.
Currently the supported device is the i1Studio from X-Rite.
The following is a step-by-step instruction.
In the main screen select the settings button
Once Settings have been selected, in the pop-up window go to the Calibrations Tab and select the profile you are using
Next, select PRINT CALIBRATED TARGET
After Target prints, allow 15 mins for drying. Once dry, make sure Spectrophotometer is calibrated. If it is not, do so now by turning the wheel so the "light" is pointing at the calibration symbol (next symbol counter-clockwise).
After calibration, select the button labeled CYAN TARGET, line up i1 studio so the "light" is positioned to start on the left of the patches starting in the white paper area and the body of the i1 Studio is lined up with the CYAN patches.
Hold the button on back side of i1 Studio, and slowly drag it across the cyan patches until the "light" has passed all the patches and rests on white paper once again. At this point, release the button. The program will let you know whether or not your scan was successful. Repeat this step for the remaining three colors.